Skip to content
ONYX

Respiratory Intelligence

ONYX — Intelligence Behind Every Breath.

Connected airflow sensing and multimodal artificial intelligence, engineered to understand the respiratory system one measurement at a time.

Explore the technologyRead the research
Scroll

01Our thesis

Every breath is a measurement. Respiratory conditions change hour to hour, shaped by airflow, environment, and biology. ONYX is building the instruments and intelligence to observe those signals together — continuously, rigorously, and personally.

Data modalities under investigation
04
Years of continuous research
05
Peer-review submissions in progress
03
Presented on the international stage
ISEF

02The platform

Three layers. One continuous understanding of respiration.

Hardware that measures, a model that learns across modalities, and a system that translates insight into structured asthma management.

ONYX connected respiratory monitoring device with a luminous cyan flow-sensor ring

Layer 01

ONYX Device

A connected airflow sensing instrument that captures peak expiratory flow and complementary respiratory parameters with every effort.

Layer 02

AsthmaNET

Multimodal AI research integrating airflow, environment, cough audio, and genomics for personalized risk modeling.

Layer 03

ACMS

The Asthma Control and Management System — longitudinal tracking, contextual alerts, and structured reporting for patients and care teams.

Signal

Flow-volume loop

Illustrative
VOLUME (L)FLOW (L/s)PEF

Drag to rotate

03Physiology first

Designed around the architecture of the airway.

Peak expiratory flow reflects how freely air moves through a branching network of more than twenty generations of airways. ONYX models that system as a whole — the luminous pulse traces a breath from the trachea to the distal bronchioles.

01
Trachea → BronchiConducting airways where expiratory flow is generated and limited.
02
BronchiolesPeripheral airways in which narrowing alters measurable flow dynamics.
03
ParenchymaLung volume and elastic recoil that drive the forced expiratory maneuver.

04From breath to insight

A single pipeline, from sensor to system.

  1. STEP 01

    Capture

    A forced exhalation through the ONYX device is sampled by a precision airflow sensor, yielding peak expiratory flow and complementary parameters.

    VOLUME (L)FLOW (L/s)PEF
  2. STEP 02

    Contextualize

    Each measurement is time-aligned with environmental conditions and, where consented, cough audio and genomic information.

    Airflow

    PEF series

    Environment

    AQI · Pollen · RH

    Cough audio

    Spectrogram

    Genomics

    Variant features

  3. STEP 03

    Interpret

    AsthmaNET encodes every modality independently, then fuses them to investigate individualized patterns of respiratory risk.

  4. STEP 04

    Manage

    ACMS organizes longitudinal trends into structured, shareable summaries designed to support conversations with clinicians.

    Weekly summaryConcept
    TrendVariabilityAdherence

05Research lineage

From a regional fair to the international stage.

Five years of iterative research, refined under expert judging at every level of competition before entering formal peer review.

The full research story
  1. Research displays at the Orange County Science and Engineering Fair

    Stage 01 · Regional

    OCSEF

    Orange County Science & Engineering Fair

  2. Exhibition hall at the California Science and Engineering Fair

    Stage 02 · State

    CSEF

    California Science & Engineering Fair

  3. International Science and Engineering Fair convention hall with international flags

    Stage 03 · International

    ISEF

    Regeneron International Science & Engineering Fair

Build the future of respiratory medicine with us.

ONYX collaborates with researchers, clinicians, and industry partners who share a commitment to scientific rigor.

Start a conversationkourosh@onyx.directory